VEGF-C is a member of VEGF family, acts as a highly specific mitogen and serves as the stimulation of vessels and lymphatic ducts formation. 近年来发现的血管内皮生长因子C(VEGF-C)是血管内皮生长因子(VEGF)家族的新成员,是一种高度特异的血管内皮细胞有丝分裂原,具有刺激血管和淋巴管生成的双重作用。
Malignant tumor is characterized by the metastasis of tumor cells via vessels and lymphatic ducts. 肿瘤细胞通过血管及淋巴管向其它器官扩散是恶性肿瘤的主要生物学特征。
The mechanism of tumor induced formation of lymphatic ducts and its role in the development of metastasis is still unclear. 然而,关于肿瘤诱导的淋巴管生成的具体机制及其在肿瘤发展转移中的作用均未阐明。